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CREG ameliorates the phenotypic switching of cardiac fibroblasts after myocardial infarction via modulation of CDC42

Phenotype switching of cardiac fibroblasts into myofibroblasts plays important role in cardiac fibrosis following myocardial infarction (MI). Cellular repressor of E1A-stimulated genes (CREG) protects against vascular and cardiac remodeling induced by angiotensin-II. However, the effects and mechani...

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Detalles Bibliográficos
Autores principales: Liu, Dan, Tian, Xiaoxiang, Liu, Yanxia, Song, Haixu, Cheng, Xiaoli, Zhang, Xiaolin, Yan, Chenghui, Han, Yaling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8024263/
https://www.ncbi.nlm.nih.gov/pubmed/33824277
http://dx.doi.org/10.1038/s41419-021-03623-w