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Development of a bispecific immune engager using a recombinant malaria protein

As an immune evasion and survival strategy, the Plasmodium falciparum malaria parasite has evolved a protein named VAR2CSA. This protein mediates sequestration of infected red blood cells in the placenta through the interaction with a unique carbohydrate abundantly and exclusively present in the pla...

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Detalles Bibliográficos
Autores principales: Nordmaj, Mie A., Roberts, Morgan E., Sachse, Emilie S., Dagil, Robert, Andersen, Anne Poder, Skeltved, Nanna, Grunddal, Kaare V., Erdoğan, Sayit Mahmut, Choudhary, Swati, Gustsavsson, Tobias, Ørum-Madsen, Maj Sofie, Moskalev, Igor, Tian, Weihua, Yang, Zhang, Clausen, Thomas M., Theander, Thor G., Daugaard, Mads, Nielsen, Morten A., Salanti, Ali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8024270/
https://www.ncbi.nlm.nih.gov/pubmed/33824272
http://dx.doi.org/10.1038/s41419-021-03611-0