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Maheshvara regulates JAK/STAT signaling by interacting and stabilizing hopscotch transcripts which leads to apoptosis in Drosophila melanogaster

Maheshvara (mahe), an RNA helicase that is widely conserved across taxa, regulates Notch signaling and neuronal development in Drosophila. In order to identify novel components regulated by mahe, transcriptome profiling of ectopic mahe was carried out and this revealed striking upregulation of JAK/S...

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Detalles Bibliográficos
Autores principales: Maurya, Bhawana, Surabhi, Satya, Das, Rituparna, Pandey, Pranjali, Mukherjee, Ashim, Mutsuddi, Mousumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8024297/
https://www.ncbi.nlm.nih.gov/pubmed/33824299
http://dx.doi.org/10.1038/s41419-021-03649-0