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Tubulin acetylation enhances lung cancer resistance to paclitaxel-induced cell death through Mcl-1 stabilization

The posttranslational modifications (PTMs) of microtubules have been reported to play an important role in cancer aggressiveness, including apoptosis resistance. In this study, we aimed to investigate the biological role of microtubule PTMs in the regulation of paclitaxel responsiveness. The acetyla...

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Detalles Bibliográficos
Autores principales: Wattanathamsan, Onsurang, Thararattanobon, Rawikorn, Rodsiri, Ratchanee, Chanvorachote, Pithi, Vinayanuwattikun, Chanida, Pongrakhananon, Varisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8024319/
https://www.ncbi.nlm.nih.gov/pubmed/33824297
http://dx.doi.org/10.1038/s41420-021-00453-9