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Tubulin acetylation enhances lung cancer resistance to paclitaxel-induced cell death through Mcl-1 stabilization
The posttranslational modifications (PTMs) of microtubules have been reported to play an important role in cancer aggressiveness, including apoptosis resistance. In this study, we aimed to investigate the biological role of microtubule PTMs in the regulation of paclitaxel responsiveness. The acetyla...
Autores principales: | Wattanathamsan, Onsurang, Thararattanobon, Rawikorn, Rodsiri, Ratchanee, Chanvorachote, Pithi, Vinayanuwattikun, Chanida, Pongrakhananon, Varisa |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8024319/ https://www.ncbi.nlm.nih.gov/pubmed/33824297 http://dx.doi.org/10.1038/s41420-021-00453-9 |
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