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AMPK activation by ASP4132 inhibits non-small cell lung cancer cell growth

Activation of adenosine monophosphate-activated protein kinase (AMPK) is able to produce significant anti-non-small cell lung cancer (NSCLC) cell activity. ASP4132 is an orally active and highly effective AMPK activator. The current study tested its activity against NSCLC cells. In primary NSCLC cel...

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Detalles Bibliográficos
Autores principales: Xia, Ying-chen, Zha, Jian-hua, Sang, Yong-Hua, Yin, Hui, Xu, Guo-qiu, Zhen, Jie, Zhang, Yan, Yu, Ben-tong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8024326/
https://www.ncbi.nlm.nih.gov/pubmed/33824293
http://dx.doi.org/10.1038/s41419-021-03655-2