T cell assays differentiate clinical and subclinical SARS-CoV-2 infections from cross-reactive antiviral responses

Identification of protective T cell responses against SARS-CoV-2 requires distinguishing people infected with SARS-CoV-2 from those with cross-reactive immunity to other coronaviruses. Here we show a range of T cell assays that differentially capture immune function to characterise SARS-CoV-2 respon...

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Detalles Bibliográficos
Autores principales: Ogbe, Ane, Kronsteiner, Barbara, Skelly, Donal T., Pace, Matthew, Brown, Anthony, Adland, Emily, Adair, Kareena, Akhter, Hossain Delowar, Ali, Mohammad, Ali, Serat-E, Angyal, Adrienn, Ansari, M. Azim, Arancibia-Cárcamo, Carolina V., Brown, Helen, Chinnakannan, Senthil, Conlon, Christopher, de Lara, Catherine, de Silva, Thushan, Dold, Christina, Dong, Tao, Donnison, Timothy, Eyre, David, Flaxman, Amy, Fletcher, Helen, Gardner, Joshua, Grist, James T., Hackstein, Carl-Philipp, Jaruthamsophon, Kanoot, Jeffery, Katie, Lambe, Teresa, Lee, Lian, Li, Wenqin, Lim, Nicholas, Matthews, Philippa C., Mentzer, Alexander J., Moore, Shona C., Naisbitt, Dean J., Ogese, Monday, Ogg, Graham, Openshaw, Peter, Pirmohamed, Munir, Pollard, Andrew J., Ramamurthy, Narayan, Rongkard, Patpong, Rowland-Jones, Sarah, Sampson, Oliver, Screaton, Gavin, Sette, Alessandro, Stafford, Lizzie, Thompson, Craig, Thomson, Paul J., Thwaites, Ryan, Vieira, Vinicius, Weiskopf, Daniela, Zacharopoulou, Panagiota, Turtle, Lance, Klenerman, Paul, Goulder, Philip, Frater, John, Barnes, Eleanor, Dunachie, Susanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8024333/
https://www.ncbi.nlm.nih.gov/pubmed/33824342
http://dx.doi.org/10.1038/s41467-021-21856-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8024333/
https://www.ncbi.nlm.nih.gov/pubmed/33824342
http://dx.doi.org/10.1038/s41467-021-21856-3

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