C3G downregulation induces the acquisition of a mesenchymal phenotype that enhances aggressiveness of glioblastoma cells

Glioblastoma (GBM) is the most aggressive tumor from the central nervous system (CNS). The current lack of efficient therapies makes essential to find new treatment strategies. C3G, a guanine nucleotide exchange factor for some Ras proteins, plays a dual role in cancer, but its function in GBM remai...

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Detalles Bibliográficos
Autores principales: Manzano, Sara, Gutierrez-Uzquiza, Alvaro, Bragado, Paloma, Sequera, Celia, Herranz, Óscar, Rodrigo-Faus, María, Jauregui, Patricia, Morgner, Stephanie, Rubio, Ignacio, Guerrero, Carmen, Porras, Almudena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8024353/
https://www.ncbi.nlm.nih.gov/pubmed/33824275
http://dx.doi.org/10.1038/s41419-021-03631-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8024353/
https://www.ncbi.nlm.nih.gov/pubmed/33824275
http://dx.doi.org/10.1038/s41419-021-03631-w

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