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C3G downregulation induces the acquisition of a mesenchymal phenotype that enhances aggressiveness of glioblastoma cells
Glioblastoma (GBM) is the most aggressive tumor from the central nervous system (CNS). The current lack of efficient therapies makes essential to find new treatment strategies. C3G, a guanine nucleotide exchange factor for some Ras proteins, plays a dual role in cancer, but its function in GBM remai...
Autores principales: | Manzano, Sara, Gutierrez-Uzquiza, Alvaro, Bragado, Paloma, Sequera, Celia, Herranz, Óscar, Rodrigo-Faus, María, Jauregui, Patricia, Morgner, Stephanie, Rubio, Ignacio, Guerrero, Carmen, Porras, Almudena |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8024353/ https://www.ncbi.nlm.nih.gov/pubmed/33824275 http://dx.doi.org/10.1038/s41419-021-03631-w |
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