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Biochemical and structural characterization of the BioZ enzyme engaged in bacterial biotin synthesis pathway

Biotin is an essential micro-nutrient across the three domains of life. The paradigm earlier step of biotin synthesis denotes “BioC-BioH” pathway in Escherichia coli. Here we report that BioZ bypasses the canonical route to begin biotin synthesis. In addition to its origin of Rhizobiales, protein ph...

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Detalles Bibliográficos
Autores principales: Zhang, Sitao, Xu, Yongchang, Guan, Hongxin, Cui, Tao, Liao, Yuling, Wei, Wenhui, Li, Jun, Hassan, Bachar H., Zhang, Huimin, Jia, Xu, Ouyang, Songying, Feng, Youjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8024396/
https://www.ncbi.nlm.nih.gov/pubmed/33824341
http://dx.doi.org/10.1038/s41467-021-22360-4