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Solubility of Ketoconazole (antifungal drug) in SC-CO(2) for binary and ternary systems: measurements and empirical correlations
One of the main steps in choosing the drug nanoparticle production processes by supercritical carbon dioxide (SC-CO(2)) is determining the solubility of the solid solute. For this purpose, the solubility of Ketoconazole (KTZ) in the SC-CO(2), binary system, as well as in the SC-CO(2)-menthol (cosolv...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8024397/ https://www.ncbi.nlm.nih.gov/pubmed/33824375 http://dx.doi.org/10.1038/s41598-021-87243-6 |