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Solubility of Ketoconazole (antifungal drug) in SC-CO(2) for binary and ternary systems: measurements and empirical correlations

One of the main steps in choosing the drug nanoparticle production processes by supercritical carbon dioxide (SC-CO(2)) is determining the solubility of the solid solute. For this purpose, the solubility of Ketoconazole (KTZ) in the SC-CO(2), binary system, as well as in the SC-CO(2)-menthol (cosolv...

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Detalles Bibliográficos
Autores principales: Sodeifian, Gholamhossein, Sajadian, Seyed Ali, Razmimanesh, Fariba, Hazaveie, Seyed Mojtaba
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8024397/
https://www.ncbi.nlm.nih.gov/pubmed/33824375
http://dx.doi.org/10.1038/s41598-021-87243-6