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Cytotoxic T-lymphocyte infiltration and chemokine predict long-term patient survival independently of tumor mutational burden in triple-negative breast cancer

BACKGROUND: Cytotoxic T-lymphocyte (CTL) infiltration into tumor is a positive prognostic factor in breast cancer. High tumor mutational burden (TMB) is also considered as a predictor of tumor immunogenicity and response to immunotherapy. However, it is unclear whether the infiltration of functional...

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Detalles Bibliográficos
Autores principales: Katsuta, Eriko, Yan, Li, Opyrchal, Mateusz, Kalinski, Pawel, Takabe, Kazuaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8024454/
https://www.ncbi.nlm.nih.gov/pubmed/33868461
http://dx.doi.org/10.1177/17588359211006680