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A Phase II Randomized Clinical Trial and Mechanistic Studies Using Improved Probiotics to Prevent Oral Mucositis Induced by Concurrent Radiotherapy and Chemotherapy in Nasopharyngeal Carcinoma

Earlier evidence has proven that probiotic supplements can reduce concurrent chemoradiotherapy (CCRT)-induced oral mucositis (OM) in nasopharyngeal cancer (NPC). The incidence of severe OM (grade 3 or higher) was the primary endpoint in this study. We first enrolled 85 patients with locally advanced...

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Detalles Bibliográficos
Autores principales: Xia, Chaofei, Jiang, Chunling, Li, Wenyu, Wei, Jing, Hong, Hu, Li, Jingao, Feng, Liu, Wei, Hong, Xin, Hongbo, Chen, Tingtao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8024544/
https://www.ncbi.nlm.nih.gov/pubmed/33841399
http://dx.doi.org/10.3389/fimmu.2021.618150