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Voltage Gated Sodium Channel Genes in Epilepsy: Mutations, Functional Studies, and Treatment Dimensions

Genetic epilepsy occurs as a result of mutations in either a single gene or an interplay of different genes. These mutations have been detected in ion channel and non-ion channel genes. A noteworthy class of ion channel genes are the voltage gated sodium channels (VGSCs) that play key roles in the d...

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Detalles Bibliográficos
Autores principales: Ademuwagun, Ibitayo Abigail, Rotimi, Solomon Oladapo, Syrbe, Steffen, Ajamma, Yvonne Ukamaka, Adebiyi, Ezekiel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8024648/
https://www.ncbi.nlm.nih.gov/pubmed/33841294
http://dx.doi.org/10.3389/fneur.2021.600050