Mauve/LYST limits fusion of lysosome-related organelles and promotes centrosomal recruitment of microtubule nucleating proteins

Lysosome-related organelles (LROs) are endosomal compartments carrying tissue-specific proteins, which become enlarged in Chediak-Higashi syndrome (CHS) due to mutations in LYST. Here, we show that Drosophila Mauve, a counterpart of LYST, suppresses vesicle fusion events with lipid droplets (LDs) du...

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Detalles Bibliográficos
Autores principales: Lattao, Ramona, Rangone, Hélène, Llamazares, Salud, Glover, David M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8024676/
https://www.ncbi.nlm.nih.gov/pubmed/33725482
http://dx.doi.org/10.1016/j.devcel.2021.02.019

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8024676/
https://www.ncbi.nlm.nih.gov/pubmed/33725482
http://dx.doi.org/10.1016/j.devcel.2021.02.019

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