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High-altitude deer mouse hypoxia-inducible factor-2α shows defective interaction with CREB-binding protein

Numerous mammalian species have adapted to the chronic hypoxia of high altitude. Recent genomic studies have identified evidence for natural selection of genes and associated genetic changes in these species. A major gap in our knowledge is an understanding of the functional significance, if any, of...

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Detalles Bibliográficos
Autores principales: Song, Daisheng, Bigham, Abigail W., Lee, Frank S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8024697/
https://www.ncbi.nlm.nih.gov/pubmed/33639161
http://dx.doi.org/10.1016/j.jbc.2021.100461