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Structural characterization of a PCP–R didomain from an archaeal nonribosomal peptide synthetase reveals novel interdomain interactions

Nonribosomal peptide synthetases (NRPSs) are multimodular enzymes that produce a wide range of bioactive peptides, such as siderophores, toxins, and antibacterial and insecticidal agents. NRPSs are dynamic proteins characterized by extensive interdomain communications as a consequence of their assem...

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Detalles Bibliográficos
Autores principales: Deshpande, Sandesh, Altermann, Eric, Sarojini, Vijayalekshmi, Lott, J. Shaun, Lee, T. Verne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8024701/
https://www.ncbi.nlm.nih.gov/pubmed/33610550
http://dx.doi.org/10.1016/j.jbc.2021.100432