Merlin deficiency alters the redox management program in breast cancer

The expression of Merlin tumor suppressor protein encoded by Neurofibromin 2 (NF2) gene is remarkably decreased in metastatic breast cancer tissues. In order to recapitulate clinical evidence, we generated a unique, conditional Nf2‐knockout (Nf2(−/−)) mouse mammary tumor model. Merlin‐deficient brea...

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Detalles Bibliográficos
Autores principales: Mota, Mateus, Metge, Brandon J., Hinshaw, Dominique C., Alsheikh, Heba A., Chen, Dongquan, Samant, Rajeev S., Shevde, Lalita A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8024723/
https://www.ncbi.nlm.nih.gov/pubmed/33410252
http://dx.doi.org/10.1002/1878-0261.12896

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8024723/
https://www.ncbi.nlm.nih.gov/pubmed/33410252
http://dx.doi.org/10.1002/1878-0261.12896

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