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Regulation of MRE11A by UBQLN4 leads to cisplatin resistance in patients with esophageal squamous cell carcinoma

Resistance to standard cisplatin‐based chemotherapies leads to worse survival outcomes for patients with esophageal squamous cell carcinoma (ESCC). Therefore, there is an urgent need to understand the aberrant mechanisms driving resistance in ESCC tumors. We hypothesized that ubiquilin‐4 (UBQLN4), a...

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Detalles Bibliográficos
Autores principales: Murakami, Tomohiro, Shoji, Yoshiaki, Nishi, Tomohiko, Chang, Shu‐Ching, Jachimowicz, Ron D., Hoshimoto, Sojun, Ono, Shigeshi, Shiloh, Yosef, Takeuchi, Hiroya, Kitagawa, Yuko, Hoon, Dave S. B., Bustos, Matias A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8024730/
https://www.ncbi.nlm.nih.gov/pubmed/33605536
http://dx.doi.org/10.1002/1878-0261.12929