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Combined over-expression of two cytochrome P450 genes exacerbates the fitness cost of pyrethroid resistance in the major African malaria vector Anopheles funestus

Metabolic resistance driven by multiple P450 genes is worsening insecticide resistance in malaria vectors. However, it remains unclear whether such multiple over-expression imposes an additive fitness cost in the vectors. Here, we showed that two highly over-expressed P450 genes (CYP6P9a and CYP6P9b...

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Detalles Bibliográficos
Autores principales: Tchouakui, Magellan, Mugenzi, Leon M.J., Wondji, Murielle J., Tchoupo, Micareme, Njiokou, Flobert, Wondji, Charles S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Academic Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8024743/
https://www.ncbi.nlm.nih.gov/pubmed/33771251
http://dx.doi.org/10.1016/j.pestbp.2021.104772