IRAK-M knockout promotes allergic airway inflammation, but not airway hyperresponsiveness, in house dust mite-induced experimental asthma model

BACKGROUND: IL-1 receptor associated-kinase (IRAK)-M, expressed by airway epithelium and macrophages, was shown to regulate acute and chronic airway inflammation exhibiting a biphasic response in an OVA-based animal model. House dust mite (HDM) is a common real-life aeroallergen highly relevant to a...

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Detalles Bibliográficos
Autores principales: Zhang, Xudong, Zhang, Mingqiang, Li, Lun, Chen, Wei, Zhou, Wexun, Gao, Jinming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8024803/
https://www.ncbi.nlm.nih.gov/pubmed/33841934
http://dx.doi.org/10.21037/jtd-20-2133

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8024803/
https://www.ncbi.nlm.nih.gov/pubmed/33841934
http://dx.doi.org/10.21037/jtd-20-2133

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