Tunable, division-independent control of gene activation timing by a polycomb switch

During development, progenitors often differentiate many cell generations after receiving signals. These delays must be robust yet tunable for precise population size control. Polycomb repressive mechanisms, involving histone H3 lysine-27 trimethylation (H3K27me3), restrain the expression of lineage...

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Detalles Bibliográficos
Autores principales: Pease, Nicholas A., Nguyen, Phuc H.B., Woodworth, Marcus A., Ng, Kenneth K.H., Irwin, Blythe, Vaughan, Joshua C., Kueh, Hao Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8024876/
https://www.ncbi.nlm.nih.gov/pubmed/33761349
http://dx.doi.org/10.1016/j.celrep.2021.108888

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8024876/
https://www.ncbi.nlm.nih.gov/pubmed/33761349
http://dx.doi.org/10.1016/j.celrep.2021.108888

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