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Tunable, division-independent control of gene activation timing by a polycomb switch
During development, progenitors often differentiate many cell generations after receiving signals. These delays must be robust yet tunable for precise population size control. Polycomb repressive mechanisms, involving histone H3 lysine-27 trimethylation (H3K27me3), restrain the expression of lineage...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8024876/ https://www.ncbi.nlm.nih.gov/pubmed/33761349 http://dx.doi.org/10.1016/j.celrep.2021.108888 |