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Mimicking and surpassing the xenograft model with cancer-on-chip technology

Organs-on-chips are in vitro models in which human tissues are cultured in microfluidic compartments with a controlled, dynamic micro-environment. Specific organs-on-chips are being developed to mimic human tumors, but the validation of such ‘cancer-on-chip’ models for use in drug development is ham...

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Detalles Bibliográficos
Autores principales: Komen, Job, van Neerven, Sanne M., van den Berg, Albert, Vermeulen, Louis, van der Meer, Andries D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8024912/
https://www.ncbi.nlm.nih.gov/pubmed/33773183
http://dx.doi.org/10.1016/j.ebiom.2021.103303