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Mimicking and surpassing the xenograft model with cancer-on-chip technology
Organs-on-chips are in vitro models in which human tissues are cultured in microfluidic compartments with a controlled, dynamic micro-environment. Specific organs-on-chips are being developed to mimic human tumors, but the validation of such ‘cancer-on-chip’ models for use in drug development is ham...
Autores principales: | Komen, Job, van Neerven, Sanne M., van den Berg, Albert, Vermeulen, Louis, van der Meer, Andries D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8024912/ https://www.ncbi.nlm.nih.gov/pubmed/33773183 http://dx.doi.org/10.1016/j.ebiom.2021.103303 |
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