Cargando…

A human ACTH-secreting corticotroph tumoroid model: Novel Human ACTH-Secreting Tumor Cell in vitro Model

BACKGROUND: Cushing disease (CD), although rare, is a life-threatening disorder caused by an adrenocorticotropic hormone (ACTH)-secreting pituitary adenoma, which leads to excess adrenal-derived cortisol. Efficacious and safe medical therapies that control both hormonal hypersecretion and pituitary...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Dongyun, Hugo, Willy, Redublo, Peter, Miao, Hui, Bergsneider, Marvin, Wang, Marilene B., Kim, Won, Yong, William H., Heaney, Anthony P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8024915/
https://www.ncbi.nlm.nih.gov/pubmed/33773184
http://dx.doi.org/10.1016/j.ebiom.2021.103294