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Basic mechanism of the autonomous ClpG disaggregase

Bacterial survival during lethal heat stress relies on the cellular ability to reactivate aggregated proteins. This activity is typically executed by the canonical 70-kDa heat shock protein (Hsp70)–ClpB bichaperone disaggregase, which is most widespread in bacteria. The ClpB disaggregase is a member...

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Detalles Bibliográficos
Autores principales: Katikaridis, Panagiotis, Römling, Ute, Mogk, Axel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8024975/
https://www.ncbi.nlm.nih.gov/pubmed/33639171
http://dx.doi.org/10.1016/j.jbc.2021.100460