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Asymmetric Cell Division of Fibroblasts is An Early Deterministic Step to Generate Elite Cells during Cell Reprogramming

Cell reprogramming is considered a stochastic process, and it is not clear which cells are prone to be reprogrammed and whether a deterministic step exists. Here, asymmetric cell division (ACD) at the early stage of induced neuronal (iN) reprogramming is shown to play a deterministic role in generat...

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Detalles Bibliográficos
Autores principales: Song, Yang, Soto, Jennifer, Wang, Pingping, An, Qin, Zhang, Xuexiang, Hong, SoonGweon, Lee, Luke P., Fan, Guoping, Yang, Li, Li, Song
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8025021/
https://www.ncbi.nlm.nih.gov/pubmed/33854891
http://dx.doi.org/10.1002/advs.202003516