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Intraepithelial Lymphocytes Suppress Intestinal Tumor Growth by Cell-to-Cell Contact via CD103/E-Cadherin Signal

BACKGROUND & AIMS: The reason why small intestinal cancer is rarer than colorectal cancer is not clear. We hypothesized that intraepithelial lymphocytes (IELs), which are enriched in the small intestine, are the closest immune cells to epithelial cells, exclude tumor cells via cell-to-cell conta...

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Detalles Bibliográficos
Autores principales: Morikawa, Ryo, Nemoto, Yasuhiro, Yonemoto, Yuki, Tanaka, Shohei, Takei, Yuria, Oshima, Shigeru, Nagaishi, Takashi, Tsuchiya, Kiichiro, Nozaki, Kengo, Mizutani, Tomohiro, Nakamura, Tetsuya, Watanabe, Mamoru, Okamoto, Ryuichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8025200/
https://www.ncbi.nlm.nih.gov/pubmed/33515805
http://dx.doi.org/10.1016/j.jcmgh.2021.01.014