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Intraepithelial Lymphocytes Suppress Intestinal Tumor Growth by Cell-to-Cell Contact via CD103/E-Cadherin Signal
BACKGROUND & AIMS: The reason why small intestinal cancer is rarer than colorectal cancer is not clear. We hypothesized that intraepithelial lymphocytes (IELs), which are enriched in the small intestine, are the closest immune cells to epithelial cells, exclude tumor cells via cell-to-cell conta...
Autores principales: | Morikawa, Ryo, Nemoto, Yasuhiro, Yonemoto, Yuki, Tanaka, Shohei, Takei, Yuria, Oshima, Shigeru, Nagaishi, Takashi, Tsuchiya, Kiichiro, Nozaki, Kengo, Mizutani, Tomohiro, Nakamura, Tetsuya, Watanabe, Mamoru, Okamoto, Ryuichi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8025200/ https://www.ncbi.nlm.nih.gov/pubmed/33515805 http://dx.doi.org/10.1016/j.jcmgh.2021.01.014 |
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