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Palmitate reduces starvation-induced ER stress by inhibiting ER-phagy in hypothalamic cells
Palmitate is a saturated fatty acid that is well known to induce endoplasmic reticulum (ER) stress and autophagy. A high-fat diet increases the palmitate level in the hypothalamus, the main region of the brain regulating energy metabolism. Interestingly, hypothalamic palmitate level is also increase...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8025501/ https://www.ncbi.nlm.nih.gov/pubmed/33823883 http://dx.doi.org/10.1186/s13041-021-00777-8 |