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Palmitate reduces starvation-induced ER stress by inhibiting ER-phagy in hypothalamic cells

Palmitate is a saturated fatty acid that is well known to induce endoplasmic reticulum (ER) stress and autophagy. A high-fat diet increases the palmitate level in the hypothalamus, the main region of the brain regulating energy metabolism. Interestingly, hypothalamic palmitate level is also increase...

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Detalles Bibliográficos
Autores principales: Lim, Yun, Kim, Seolsong, Kim, Eun-Kyoung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8025501/
https://www.ncbi.nlm.nih.gov/pubmed/33823883
http://dx.doi.org/10.1186/s13041-021-00777-8