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Sulfobutylether-beta-cyclodextrin-enabled antiviral remdesivir: Characterization of electrospun- and lyophilized formulations

Veklury™ by Gilead Sciences, Inc., containing antiviral drug, remdesivir (REM) has received emergency authorization in the USA and in Europe for COVID-19 therapy. Here, for the first time, we describe details of the non-covalent, host-guest type interaction between REM and the solubilizing excipient...

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Detalles Bibliográficos
Autores principales: Szente, Lajos, Puskás, István, Sohajda, Tamás, Varga, Erzsébet, Vass, Panna, Nagy, Zsombor Kristóf, Farkas, Attila, Várnai, Bianka, Béni, Szabolcs, Hazai, Eszter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8025548/
https://www.ncbi.nlm.nih.gov/pubmed/33910715
http://dx.doi.org/10.1016/j.carbpol.2021.118011