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Hybrid Chemo-, Bio-, and Electrocatalysis for Atom-Efficient Deuteration of Cofactors in Heavy Water
[Image: see text] Deuterium-labeled nicotinamide cofactors such as [4-(2)H]-NADH can be used as mechanistic probes in biological redox processes and offer a route to the synthesis of selectively [(2)H] labeled chemicals via biocatalytic reductive deuteration. Atom-efficient routes to the formation a...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical Society
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8025731/ https://www.ncbi.nlm.nih.gov/pubmed/33842020 http://dx.doi.org/10.1021/acscatal.0c03437 |