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Protein identification from electron cryomicroscopy maps by automated model building and side-chain matching

Using single-particle electron cryo-microscopy (cryo-EM), it is possible to obtain multiple reconstructions showing the 3D structures of proteins imaged as a mixture. Here, it is shown that automatic map interpretation based on such reconstructions can be used to create atomic models of proteins as...

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Detalles Bibliográficos
Autores principales: Terwilliger, Thomas C., Sobolev, Oleg V., Afonine, Pavel V., Adams, Paul D., Ho, Chi-Min, Li, Xiaorun, Zhou, Z. Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8025881/
https://www.ncbi.nlm.nih.gov/pubmed/33825706
http://dx.doi.org/10.1107/S2059798321001765