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Vagabond: bond-based parametrization reduces overfitting for refinement of proteins
Structural biology methods have delivered over 150 000 high-resolution structures of macromolecules, which have fundamentally altered our understanding of biology and our approach to developing new medicines. However, the description of molecular flexibility is instrinsically flawed and in almost al...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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International Union of Crystallography
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8025884/ https://www.ncbi.nlm.nih.gov/pubmed/33825703 http://dx.doi.org/10.1107/S2059798321000826 |