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Deducing high-accuracy protein contact-maps from a triplet of coevolutionary matrices through deep residual convolutional networks

The topology of protein folds can be specified by the inter-residue contact-maps and accurate contact-map prediction can help ab initio structure folding. We developed TripletRes to deduce protein contact-maps from discretized distance profiles by end-to-end training of deep residual neural-networks...

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Detalles Bibliográficos
Autores principales: Li, Yang, Zhang, Chengxin, Bell, Eric W., Zheng, Wei, Zhou, Xiaogen, Yu, Dong-Jun, Zhang, Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8026059/
https://www.ncbi.nlm.nih.gov/pubmed/33770072
http://dx.doi.org/10.1371/journal.pcbi.1008865