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Structure of TFIIK for phosphorylation of CTD of RNA polymerase II

During transcription initiation, the general transcription factor TFIIH marks RNA polymerase II by phosphorylating Ser5 of the carboxyl-terminal domain (CTD) of Rpb1, which is followed by extensive modifications coupled to transcription elongation, mRNA processing, and histone dynamics. We have dete...

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Detalles Bibliográficos
Autores principales: van Eeuwen, Trevor, Li, Tao, Kim, Hee Jong, Gorbea Colón, Jose J., Parker, Mitchell I., Dunbrack, Roland L., Garcia, Benjamin A., Tsai, Kuang-Lei, Murakami, Kenji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8026125/
https://www.ncbi.nlm.nih.gov/pubmed/33827808
http://dx.doi.org/10.1126/sciadv.abd4420