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Structure of TFIIK for phosphorylation of CTD of RNA polymerase II
During transcription initiation, the general transcription factor TFIIH marks RNA polymerase II by phosphorylating Ser5 of the carboxyl-terminal domain (CTD) of Rpb1, which is followed by extensive modifications coupled to transcription elongation, mRNA processing, and histone dynamics. We have dete...
Autores principales: | van Eeuwen, Trevor, Li, Tao, Kim, Hee Jong, Gorbea Colón, Jose J., Parker, Mitchell I., Dunbrack, Roland L., Garcia, Benjamin A., Tsai, Kuang-Lei, Murakami, Kenji |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8026125/ https://www.ncbi.nlm.nih.gov/pubmed/33827808 http://dx.doi.org/10.1126/sciadv.abd4420 |
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