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Astrocytes and neurons share region-specific transcriptional signatures that confer regional identity to neuronal reprogramming

Neural cell diversity is essential to endow distinct brain regions with specific functions. During development, progenitors within these regions are characterized by specific gene expression programs, contributing to the generation of diversity in postmitotic neurons and astrocytes. While the region...

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Detalles Bibliográficos
Autores principales: Herrero-Navarro, Álvaro, Puche-Aroca, Lorenzo, Moreno-Juan, Verónica, Sempere-Ferràndez, Alejandro, Espinosa, Ana, Susín, Rafael, Torres-Masjoan, Laia, Leyva-Díaz, Eduardo, Karow, Marisa, Figueres-Oñate, María, López-Mascaraque, Laura, López-Atalaya, José P., Berninger, Benedikt, López-Bendito, Guillermina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8026135/
https://www.ncbi.nlm.nih.gov/pubmed/33827819
http://dx.doi.org/10.1126/sciadv.abe8978