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Astrocytes and neurons share region-specific transcriptional signatures that confer regional identity to neuronal reprogramming
Neural cell diversity is essential to endow distinct brain regions with specific functions. During development, progenitors within these regions are characterized by specific gene expression programs, contributing to the generation of diversity in postmitotic neurons and astrocytes. While the region...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8026135/ https://www.ncbi.nlm.nih.gov/pubmed/33827819 http://dx.doi.org/10.1126/sciadv.abe8978 |