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GABA transporter sustains IL-1β production in macrophages

Accumulating evidence shows that nervous system governs host immune responses; however, how γ-aminobutyric acid (GABA)ergic system shapes the function of innate immune cells is poorly defined. Here, we demonstrate that GABA transporter (GAT2) modulates the macrophage function. GAT2 deficiency lowers...

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Detalles Bibliográficos
Autores principales: Xia, Yaoyao, He, Fang, Wu, Xiaoyan, Tan, Bie, Chen, Siyuan, Liao, Yuexia, Qi, Ming, Chen, Shuai, Peng, Yuanyi, Yin, Yulong, Ren, Wenkai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8026138/
https://www.ncbi.nlm.nih.gov/pubmed/33827820
http://dx.doi.org/10.1126/sciadv.abe9274