Macrophage-derived PDGF-B induces muscularization in murine and human pulmonary hypertension

Excess macrophages and smooth muscle cells (SMCs) characterize many cardiovascular diseases, but crosstalk between these cell types is poorly defined. Pulmonary hypertension (PH) is a lethal disease in which lung arteriole SMCs proliferate and migrate, coating the normally unmuscularized distal arte...

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Detalles Bibliográficos
Autores principales: Ntokou, Aglaia, Dave, Jui M., Kauffman, Amy C., Sauler, Maor, Ryu, Changwan, Hwa, John, Herzog, Erica L., Singh, Inderjit, Saltzman, W. Mark, Greif, Daniel M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8026182/
https://www.ncbi.nlm.nih.gov/pubmed/33591958
http://dx.doi.org/10.1172/jci.insight.139067

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8026182/
https://www.ncbi.nlm.nih.gov/pubmed/33591958
http://dx.doi.org/10.1172/jci.insight.139067

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