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Aging imparts cell-autonomous dysfunction to regulatory T cells during recovery from influenza pneumonia

Regulatory T (Treg) cells orchestrate resolution and repair of acute lung inflammation and injury after viral pneumonia. Compared with younger patients, older individuals experience impaired recovery and worse clinical outcomes after severe viral infections, including influenza and SARS coronavirus...

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Detalles Bibliográficos
Autores principales: Morales-Nebreda, Luisa, Helmin, Kathryn A., Torres Acosta, Manuel A., Markov, Nikolay S., Hu, Jennifer Yuan-Shih, Joudi, Anthony M., Piseaux-Aillon, Raul, Abdala-Valencia, Hiam, Politanska, Yuliya, Singer, Benjamin D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8026188/
https://www.ncbi.nlm.nih.gov/pubmed/33600379
http://dx.doi.org/10.1172/jci.insight.141690