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Aging imparts cell-autonomous dysfunction to regulatory T cells during recovery from influenza pneumonia
Regulatory T (Treg) cells orchestrate resolution and repair of acute lung inflammation and injury after viral pneumonia. Compared with younger patients, older individuals experience impaired recovery and worse clinical outcomes after severe viral infections, including influenza and SARS coronavirus...
Autores principales: | Morales-Nebreda, Luisa, Helmin, Kathryn A., Torres Acosta, Manuel A., Markov, Nikolay S., Hu, Jennifer Yuan-Shih, Joudi, Anthony M., Piseaux-Aillon, Raul, Abdala-Valencia, Hiam, Politanska, Yuliya, Singer, Benjamin D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Clinical Investigation
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8026188/ https://www.ncbi.nlm.nih.gov/pubmed/33600379 http://dx.doi.org/10.1172/jci.insight.141690 |
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