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TLR4-NLRP3-GSDMD-Mediated Pyroptosis Plays an Important Role in Aggravated Liver Injury of CD38(−/−) Sepsis Mice

Clinically, severe bacterial infection can cause septicemia and multiple organ dysfunction syndrome, especially liver injury. CD38 is closely related to many inflammatory pathways, but its role in liver injury caused by bacterial infection remains unclear. The purpose of this study is to discuss the...

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Detalles Bibliográficos
Autores principales: Zhang, Huiqing, Du, Yuna, Guo, Yujie, Wang, Zeyu, Li, Hua, Lv, Zhe, Zeng, Lifeng, Chen, Yiguo, Xie, Zhengyu, Li, Rong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8026301/
https://www.ncbi.nlm.nih.gov/pubmed/33860064
http://dx.doi.org/10.1155/2021/6687555