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Increase in Blood-Brain Barrier (BBB) Permeability Is Regulated by MMP3 via the ERK Signaling Pathway

BACKGROUND: The blood-brain barrier (BBB) regulates the exchange of molecules between the brain and peripheral blood and is composed primarily of microvascular endothelial cells (BMVECs), which form the lining of cerebral blood vessels and are linked via tight junctions (TJs). The BBB is regulated b...

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Detalles Bibliográficos
Autores principales: Zhang, Qin, Zheng, Mei, Betancourt, Cristian E., Liu, Lifeng, Sitikov, Albert, Sladojevic, Nikola, Zhao, Qiong, Zhang, John H., Liao, James K., Wu, Rongxue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8026308/
https://www.ncbi.nlm.nih.gov/pubmed/33859779
http://dx.doi.org/10.1155/2021/6655122