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Perivascular macrophages create an intravascular niche for CD8(+) T cell localisation prior to the onset of fatal experimental cerebral malaria

OBJECTIVES: The immunologic events that build up to the fatal neurological stage of experimental cerebral malaria (ECM) are incompletely understood. Here, we dissect immune cell behaviour occurring in the central nervous system (CNS) when Plasmodium berghei ANKA (PbA)‐infected mice show only minor c...

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Detalles Bibliográficos
Autores principales: Qin, Jim, Lovelace, Michael D, Mitchell, Andrew J, de Koning‐Ward, Tania, Grau, Georges ER, Pai, Saparna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8026342/
https://www.ncbi.nlm.nih.gov/pubmed/33854773
http://dx.doi.org/10.1002/cti2.1273