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Increased Hippocampal Excitability and Altered Learning Dynamics Mediate Cognitive Mapping Deficits in Human Aging

Learning the spatial layout of a novel environment is associated with dynamic activity changes in the hippocampus and in medial parietal areas. With advancing age, the ability to learn spatial environments deteriorates substantially but the underlying neural mechanisms are not well understood. Here,...

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Detalles Bibliográficos
Autores principales: Diersch, Nadine, Valdes-Herrera, Jose P., Tempelmann, Claus, Wolbers, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8026345/
https://www.ncbi.nlm.nih.gov/pubmed/33648956
http://dx.doi.org/10.1523/JNEUROSCI.0528-20.2021