Evaluating clinical impact of a shortened infusion duration for ramucirumab: a model-based approach

PURPOSE: We investigated the impact of infusion duration (30 and 60 min) on the pharmacokinetic profile of ramucirumab using a population pharmacokinetic (PopPK) modeling approach. We also assessed the relationship between infusion rate and incidence of immediate infusion-related reactions (IRRs; oc...

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Detalles Bibliográficos
Autores principales: Gao, Ling, Lau, Yiu-Keung, Wei, Ran, O’Brien, Lisa, Long, Amanda, Piao, Yongzhe, Abada, Paolo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8026424/
https://www.ncbi.nlm.nih.gov/pubmed/33532866
http://dx.doi.org/10.1007/s00280-020-04223-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8026424/
https://www.ncbi.nlm.nih.gov/pubmed/33532866
http://dx.doi.org/10.1007/s00280-020-04223-9

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