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The pharmacokinetics of [(18)F]UCB-H revisited in the healthy non-human primate brain

BACKGROUND: Positron Emission Tomography (PET) imaging of the Synaptic Vesicle glycoprotein (SV) 2A is a new tool to quantify synaptic density. [(18)F]UCB-H was one of the first promising SV2A-ligands to be labelled and used in vivo in rodent and human, while limited information on its pharmacokinet...

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Detalles Bibliográficos
Autores principales: Goutal, Sébastien, Guillermier, Martine, Becker, Guillaume, Gaudin, Mylène, Bramoullé, Yann, Luxen, André, Lemaire, Christian, Plenevaux, Alain, Salmon, Eric, Hantraye, Philippe, Barret, Olivier, Van Camp, Nadja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8026785/
https://www.ncbi.nlm.nih.gov/pubmed/33826008
http://dx.doi.org/10.1186/s13550-021-00777-8