Cargando…
The pharmacokinetics of [(18)F]UCB-H revisited in the healthy non-human primate brain
BACKGROUND: Positron Emission Tomography (PET) imaging of the Synaptic Vesicle glycoprotein (SV) 2A is a new tool to quantify synaptic density. [(18)F]UCB-H was one of the first promising SV2A-ligands to be labelled and used in vivo in rodent and human, while limited information on its pharmacokinet...
Autores principales: | Goutal, Sébastien, Guillermier, Martine, Becker, Guillaume, Gaudin, Mylène, Bramoullé, Yann, Luxen, André, Lemaire, Christian, Plenevaux, Alain, Salmon, Eric, Hantraye, Philippe, Barret, Olivier, Van Camp, Nadja |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8026785/ https://www.ncbi.nlm.nih.gov/pubmed/33826008 http://dx.doi.org/10.1186/s13550-021-00777-8 |
Ejemplares similares
-
Comparative test-retest variability of outcome parameters derived from brain [(18)F]FDG PET studies in non-human primates
por: Goutal, Sébastien, et al.
Publicado: (2020) -
Exploring with [(18)F]UCB-H the in vivo Variations in SV2A Expression through the Kainic Acid Rat Model of Temporal Lobe Epilepsy
por: Serrano, Maria Elisa, et al.
Publicado: (2020) -
Evaluating the In Vivo Specificity of [(18)F]UCB-H for the SV2A Protein, Compared with SV2B and SV2C in Rats Using microPET
por: Serrano, Maria Elisa, et al.
Publicado: (2019) -
Preclinical radiation dosimetry for the novel SV2A radiotracer [(18)F]UCB-H
por: Bretin, Florian, et al.
Publicado: (2013) -
Measuring brain synaptic vesicle protein 2A with positron emission tomography and [(18)F]UCB-H
por: Bahri, Mohamed Ali, et al.
Publicado: (2017)